‘Leaky gut’ in hematological malignancies

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

‘Leaky gut’ in hematological malignancies☆

In humans, the intestinal epithelium is a single layer of cells that constitutes one of the most important barriers between internal and external environments. The so-called ‘intestinal barrier’ (IB) is a dynamic structure composed of different types of cellular junctions that can be regulated by physiological and pathological stimuli, and act as a selective barrier to antigens and pathogens. P...

متن کامل

Leaky Gut Syndrome

The chances of being diagnosed with Leaky Gut Syndrome are pretty remote. It does not even occur to many doctors to check for the condition. A further complication is that gut distress often manifests as disease in other parts of the body. Leaky Gut Syndrome is one of the most misunderstood concepts in modern medicine. This condition is associated with an abnormal increase in the permeability o...

متن کامل

Checkpoint inhibitors in hematological malignancies

Inhibitory molecules such as PD-1, CTLA-4, LAG-3, or TIM-3 play a role to keep a balance in immune function. However, many cancers exploit such molecules to escape immune surveillance. Accumulating data support that their functions are dysregulated in lymphoid neoplasms, including plasma cell myeloma, myelodysplastic syndrome, and acute myeloid leukemia. In lymphoid neoplasms, aberrations in 9p...

متن کامل

Carbamazepine and Hematological Malignancies

Received/Geliş tarihi : May 1, 2013 Accepted/Kabul tarihi : June 10, 2013 To the Editor, The letter entitled “Carbamazepine and Multiple Myeloma: Possible Interaction”, written by Günaldı et al. [1] and published in one of the recent issues of your journal, was quite interesting. We would like to emphasize some points about that letter. In the reported case, the patient’s serum globulin level w...

متن کامل

Microsatellite instability in hematological malignancies

The genome of colorectal carcinomas displaying pronounced microsatellite instability codes for an extraordinarily high number of mutated proteins that elicit tumor-specific cellular immune responses. We have recently demonstrated that leukemic cells are also vulnerable to T cells specific for tumor-associated antigens produced in the context of microsatellite instability. This finding extends o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Revista Brasileira de Hematologia e Hemoterapia

سال: 2014

ISSN: 1516-8484

DOI: 10.1016/j.bjhh.2014.09.007